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Real-time observation of DNA looping dynamics of Type IIE restriction enzymes NaeI and NarI
Many restriction enzymes require binding of two copies of a recognition sequence for DNA cleavage, thereby introducing a loop in the DNA. We investigated looping dynamics of Type IIE restriction enzymes NaeI and NarI by tracking the Brownian motion of single tethered DNA molecules. DNA containing tw...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1326248/ https://www.ncbi.nlm.nih.gov/pubmed/16407332 http://dx.doi.org/10.1093/nar/gkj432 |