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The role of positively charged amino acids and electrostatic interactions in the complex of U1A protein and U1 hairpin II RNA

Previous kinetic investigations of the N-terminal RNA recognition motif (RRM) domain of spliceosomal protein U1A, interacting with its RNA target U1 hairpin II, provided experimental evidence for a ‘lure and lock’ model of binding in which electrostatic interactions first guide the RNA to the protei...

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Detalles Bibliográficos
Autores principales:	Law, Michael J., Linde, Michael E., Chambers, Eric J., Oubridge, Chris, Katsamba, Phinikoula S., Nilsson, Lennart, Haworth, Ian S., Laird-Offringa, Ite A.
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2006
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1326249/ https://www.ncbi.nlm.nih.gov/pubmed/16407334 http://dx.doi.org/10.1093/nar/gkj436

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