Failure to confirm influence of Methyltetrahydrofolate reductase (MTHFR) polymorphisms on age at onset of Huntington disease

BACKGROUND: Huntington disease (HD) is a fully penetrant, autosomal dominantly inherited disorder associated with abnormal expansions of a stretch of perfect CAG repeats in the 5' part of the IT15 gene. The number of repeat units is highly predictive for the age at onset (AO) of the disorder. B...

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Detalles Bibliográficos
Autores principales: Hansen, Wiebke, Saft, Carsten, Andrich, Jürgen, Müller, Thomas, Wieczorek, Stefan, Epplen, Jörg T, Arning, Larissa
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1327683/
https://www.ncbi.nlm.nih.gov/pubmed/16372906
http://dx.doi.org/10.1186/1477-5751-4-12

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1327683/
https://www.ncbi.nlm.nih.gov/pubmed/16372906
http://dx.doi.org/10.1186/1477-5751-4-12

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