Cargando…

Failure to confirm influence of Methyltetrahydrofolate reductase (MTHFR) polymorphisms on age at onset of Huntington disease

BACKGROUND: Huntington disease (HD) is a fully penetrant, autosomal dominantly inherited disorder associated with abnormal expansions of a stretch of perfect CAG repeats in the 5' part of the IT15 gene. The number of repeat units is highly predictive for the age at onset (AO) of the disorder. B...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hansen, Wiebke, Saft, Carsten, Andrich, Jürgen, Müller, Thomas, Wieczorek, Stefan, Epplen, Jörg T, Arning, Larissa
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2005
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1327683/ https://www.ncbi.nlm.nih.gov/pubmed/16372906 http://dx.doi.org/10.1186/1477-5751-4-12

Ejemplares similares

Glutathione S-Transferase Ω 1 variation does not influence age at onset of Huntington's disease
por: Arning, Larissa, et al.
Publicado: (2004)

No association between polymorphisms in the BDNF gene and age at onset in Huntington disease
por: Mai, Maren, et al.
Publicado: (2006)

Age at onset of Huntington disease is not modulated by the R72P variation in TP53 and the R196K variation in the gene coding for the human caspase activated DNase (hCAD)
por: Arning, Larissa, et al.
Publicado: (2005)

PGC-1alpha as modifier of onset age in Huntington disease
por: Taherzadeh-Fard, Elahe, et al.
Publicado: (2009)

PGC-1alpha downstream transcription factors NRF-1 and TFAM are genetic modifiers of Huntington disease
por: Taherzadeh-Fard, Elahe, et al.
Publicado: (2011)

NMDA receptor gene variations as modifiers in Huntington disease: a replication study
por: Saft, Carsten, et al.
Publicado: (2011)

Oral and dental health in Huntington‘s disease - an observational study
por: Saft, Carsten, et al.
Publicado: (2013)

Error Processing in Huntington's Disease
por: Beste, Christian, et al.
Publicado: (2006)

Time Processing in Huntington's Disease: A Group-Control Study
por: Beste, Christian, et al.
Publicado: (2007)

Folate Insufficiency Due to MTHFR Deficiency Is Bypassed by 5-Methyltetrahydrofolate
por: Vidmar Golja, Maša, et al.
Publicado: (2020)

No evidence of impaired gastric emptying in early Huntington‘s Disease
por: Saft, Carsten, et al.
Publicado: (2011)

Developing a Sensitive Platform to Measure 5-Methyltetrahydrofolate in Subjects with MTHFR and PON1 Gene Polymorphisms
por: Lu, Mong-Liang, et al.
Publicado: (2022)

Maternal methyltetrahydrofolate reductase gene mutation in patients with missed abortions
por: Rady, Helmy A.
Publicado: (2017)

Efficacy of Fumaric Acid Esters in the R6/2 and YAC128 Models of Huntington's Disease
por: Ellrichmann, Gisa, et al.
Publicado: (2011)

Pulmonary thromboembolism due to severe hyperhomocysteinemia associated with a methyltetrahydrofolate reductase mutation
por: Cho, Kyung Hoon, et al.
Publicado: (2013)

Dose-dependent improvement of myoclonic hyperkinesia due to Valproic acid in eight Huntington's Disease patients: a case series
por: Saft, Carsten, et al.
Publicado: (2006)

Association between serum 5-methyltetrahydrofolate and homocysteine in Chinese hypertensive participants with different MTHFR C677T polymorphisms: a cross-sectional study
por: Cheng, Yu, et al.
Publicado: (2022)

Altered protein phosphatase 2A methylation and Tau phosphorylation in the young and aged brain of methylenetetrahydrofolate reductase (MTHFR) deficient mice
por: Sontag, Jean-Marie, et al.
Publicado: (2014)

Methylenetetrahydrofolate Reductase (MTHFR) Gene Polymorphism and Infant’s Anthropometry at Birth
por: Aguilar-Lacasaña, Sofía, et al.
Publicado: (2021)

Methylenetetrahydrofolate Reductase (MTHFR) C677T Polymorphism and Age at Onset of Schizophrenia: No Consistent Evidence for an Association in the Nordic Population
por: Saetre, Peter, et al.
Publicado: (2012)

Resurrection of sildenafil: potential for Huntington’s Disease, too?
por: Achenbach, Jannis, et al.
Publicado: (2022)

Genomic NGFB variation and multiple sclerosis in a case control study
por: Akkad, Denis A, et al.
Publicado: (2008)

Does arterial hypertension influence the onset of Huntington's disease?
por: Valcárcel-Ocete, Leire, et al.
Publicado: (2018)

No optical coherence tomography changes in premanifest Huntington's disease mutation carriers far from disease onset
por: Schmid, Rahel Dominique, et al.
Publicado: (2022)

Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism in psoriasis in southern Turkey
por: Izmirli, Muzeyyen, et al.
Publicado: (2016)

The Role of the Immune System in Huntington's Disease
por: Ellrichmann, Gisa, et al.
Publicado: (2013)

Music perception and movement deterioration in Huntington’s disease
por: Beste, Christian, et al.
Publicado: (2011)

Effects of Periconceptional Multivitamin Supplementation on Folate and Homocysteine Levels Depending on Genetic Variants of Methyltetrahydrofolate Reductase in Infertile Japanese Women
por: Kuroda, Keiji, et al.
Publicado: (2021)

Cholecystokinin A Receptor (CCKAR) Gene Variation Is Associated with Language Lateralization
por: Ocklenburg, Sebastian, et al.
Publicado: (2013)

Frequency of SCA8, SCA10, SCA12, SCA36, FXTAS and C9orf72 repeat expansions in SCA patients negative for the most common SCA subtypes
por: Aydin, Gülsah, et al.
Publicado: (2018)

Methylenetetrahydrofolate reductase (MTHFR) polymorphisms and promoter methylation in cervical oncogenic lesions and cancer
por: Botezatu, Anca, et al.
Publicado: (2013)

Methylenetetrahydrofolate Reductase (MTHFR) Polymorphisms and Susceptibility for Cervical Lesions: A Meta-Analysis
por: Long, Shuyu, et al.
Publicado: (2012)

Age-at-onset in Huntington disease
por: Orth, Michael, et al.
Publicado: (2011)

Autosomal dominant hereditary spastic paraplegia: Novel mutations in the REEP1 gene (SPG31)
por: Schlang, Katharina J, et al.
Publicado: (2008)

Differential Diagnosis of Chorea—HIV Infection Delays Diagnosis of Huntington’s Disease by Years
por: Achenbach, Jannis, et al.
Publicado: (2021)

Phonatory Dysfunction as a Preclinical Symptom of Huntington Disease
por: Rusz, Jan, et al.
Publicado: (2014)

Serum Folate and Methylenetetrahydrofolate Reductase (MTHFR) C677T Polymorphism Adjusted for Folate Intake
por: Nishio, Kazuko, et al.
Publicado: (2008)

Association of the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism with primary glaucoma in Saudi population
por: Al-Shahrani, Hamoud, et al.
Publicado: (2016)

Polymorphism of Methylenetetrahydrofolate Reductase (MTHFR) gene and risk of Head and Neck Squamous Cell Carcinoma
por: Rodrigues, Juliana Olsen, et al.
Publicado: (2015)

Reversal of Methotrexate Toxicity in Mice by 5-Methyltetrahydrofolic Acid
por: Blair, J. A., et al.
Publicado: (1970)

Cannot write session to /tmp/vufind_sessions/sess_jvqiq32jbhj5jil697svf6v0em