Genetic Analysis of Completely Sequenced Disease-Associated MHC Haplotypes Identifies Shuffling of Segments in Recent Human History

The major histocompatibility complex (MHC) is recognised as one of the most important genetic regions in relation to common human disease. Advancement in identification of MHC genes that confer susceptibility to disease requires greater knowledge of sequence variation across the complex. Highly dupl...

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Detalles Bibliográficos
Autores principales: Traherne, James A, Horton, Roger, Roberts, Anne N, Miretti, Marcos M, Hurles, Matthew E, Stewart, C. Andrew, Ashurst, Jennifer L, Atrazhev, Alexey M, Coggill, Penny, Palmer, Sophie, Almeida, Jeff, Sims, Sarah, Wilming, Laurens G, Rogers, Jane, de Jong, Pieter J., Carrington, Mary, Elliott, John F, Sawcer, Stephen, Todd, John A, Trowsdale, John, Beck, Stephan
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1331980/
https://www.ncbi.nlm.nih.gov/pubmed/16440057
http://dx.doi.org/10.1371/journal.pgen.0020009

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