Cargando…

p66α and p66β of the Mi-2/NuRD complex mediate MBD2 and histone interaction

The Mi-2/NuRD complex is a multi-subunit protein complex with enzymatic activities involving chromatin remodeling and histone deacetylation. Targeting of Mi-2/NuRD to methylated CpG sequences mediates gene repression. The function of p66α and of p66β within the multiple subunits has not been address...

Descripción completa

Detalles Bibliográficos
Autores principales:	Brackertz, Marc, Gong, Zihua, Leers, Jörg, Renkawitz, Rainer
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2006
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1331983/ https://www.ncbi.nlm.nih.gov/pubmed/16415179 http://dx.doi.org/10.1093/nar/gkj437

Ejemplares similares

Mutants in the Mouse NuRD/Mi2 Component P66α Are Embryonic Lethal
por: Marino, Susan, et al.
Publicado: (2007)

The NuRD complex component p66 suppresses photoreceptor neuron regeneration in planarians
por: Vásquez‐Doorman, Constanza, et al.
Publicado: (2016)

Disruption of the MBD2-NuRD complex but not MBD3-NuRD induces high level HbF expression in human adult erythroid cells
por: Yu, Xiaofei, et al.
Publicado: (2019)

MBD3/NuRD Facilitates Induction of Pluripotency in a Context-Dependent Manner
por: dos Santos, Rodrigo L., et al.
Publicado: (2014)

MBD3/NuRD Facilitates Induction of Pluripotency in a Context-Dependent Manner
por: dos Santos, Rodrigo L., et al.
Publicado: (2014)

The Drosophila methyl-DNA binding protein MBD2/3 interacts with the NuRD complex via p55 and MI-2
por: Marhold, Joachim, et al.
Publicado: (2004)

Dissecting the roles of MBD2 isoforms and domains in regulating NuRD complex function during cellular differentiation
por: Schmolka, Nina, et al.
Publicado: (2023)

An intrinsically disordered region of methyl-CpG binding domain protein 2 (MBD2) recruits the histone deacetylase core of the NuRD complex
por: Desai, Megha A., et al.
Publicado: (2015)

Smek promotes corticogenesis through regulating Mbd3’s stability and Mbd3/NuRD complex recruitment to genes associated with neurogenesis
por: Moon, Byoung-San, et al.
Publicado: (2017)

A variant NuRD complex containing PWWP2A/B excludes MBD2/3 to regulate transcription at active genes
por: Zhang, Tianyi, et al.
Publicado: (2018)

Mbd3/NuRD controls lymphoid cell fate and inhibits tumorigenesis by repressing a B cell transcriptional program
por: Loughran, Stephen J., et al.
Publicado: (2017)

NuRD-interacting protein ZFP296 regulates genome-wide NuRD localization and differentiation of mouse embryonic stem cells
por: Kloet, Susan L., et al.
Publicado: (2018)

Glioma stem-like cells evade interferon suppression through MBD3/NuRD complex–mediated STAT1 downregulation
por: Zhan, Xiaoyan, et al.
Publicado: (2020)

Mbd3, a Component of NuRD/Mi-2 Complex, Helps Maintain Pluripotency of Mouse Embryonic Stem Cells by Repressing Trophectoderm Differentiation
por: Zhu, Dongmei, et al.
Publicado: (2009)

MBD2a–NuRD binds to the methylated γ-globin gene promoter and uniquely forms a complex required for silencing of HbF expression
por: Shang, Shengzhe, et al.
Publicado: (2023)

Differential roles for MBD2 and MBD3 at methylated CpG islands, active promoters and binding to exon sequences
por: Günther, Katharina, et al.
Publicado: (2013)

Specific NuRD components are required for fin regeneration in zebrafish
por: Pfefferli, Catherine, et al.
Publicado: (2014)

Chromatin Remodeling Complex NuRD in Neurodevelopment and Neurodevelopmental Disorders
por: Hoffmann, Anke, et al.
Publicado: (2019)

The topology of chromatin-binding domains in the NuRD deacetylase complex
por: Millard, Christopher J, et al.
Publicado: (2020)

The NuRD complex cooperates with SALL4 to orchestrate reprogramming
por: Wang, Bo, et al.
Publicado: (2023)

The proto-oncoprotein FBI-1 interacts with MBD3 to recruit the Mi-2/NuRD-HDAC complex and BCoR and to silence p21WAF/CDKN1A by DNA methylation
por: Choi, Won-Il, et al.
Publicado: (2013)

Histone demethylase KDM5A regulates the ZMYND8–NuRD chromatin remodeler to promote DNA repair
por: Gong, Fade, et al.
Publicado: (2017)

NuRD and CAF-1-mediated silencing of the D4Z4 array is modulated by DUX4-induced MBD3L proteins
por: Campbell, Amy E, et al.
Publicado: (2018)

Functional Analysis of Non-Genetic Resistance to Platinum in Epithelial Ovarian Cancer Reveals a Role for the MBD3-NuRD Complex in Resistance Development
por: Bauer, Tabea L., et al.
Publicado: (2021)

Biology of the Mi-2/NuRD Complex in SLAC (Stemness, Longevity/Ageing, and Cancer)
por: Zhang, Yue
Publicado: (2011)

Characterization of the nuclear import of the human CHD4–NuRD complex
por: Hoffmeister, Helen, et al.
Publicado: (2023)

The NuRD Complex in Neurodevelopment and Disease: A Case of Sliding Doors
por: Boulasiki, Paraskevi, et al.
Publicado: (2023)

The gene repressor complex NuRD interacts with the histone variant H3.3 at promoters of active genes
por: Kraushaar, Daniel C., et al.
Publicado: (2018)

The H2A.Z and NuRD associated protein HMG20A controls early head and heart developmental transcription programs
por: Herchenröther, Andreas, et al.
Publicado: (2023)

The histone demethylase LSD1 regulates inner ear progenitor differentiation through interactions with Pax2 and the NuRD repressor complex
por: Patel, Dharmeshkumar, et al.
Publicado: (2018)

The NuRD chromatin–remodeling complex regulates signaling and repair of DNA damage
por: Smeenk, Godelieve, et al.
Publicado: (2010)

CHD4 and the NuRD complex directly control cardiac sarcomere formation
por: Wilczewski, Caralynn M., et al.
Publicado: (2018)

Rational targeting of a NuRD subcomplex guided by comprehensive in situ mutagenesis
por: Sher, Falak, et al.
Publicado: (2019)

MTA3 Regulates Extravillous Trophoblast Invasion Through NuRD Complex
por: Chen, Ying, et al.
Publicado: (2017)

Mi-2/NuRD complex function is required for normal S phase progression and assembly of pericentric heterochromatin
por: Sims, Jennifer K., et al.
Publicado: (2011)

Zeb2 Recruits HDAC-NuRD to Inhibit Notch and Controls Schwann Cell Differentiation and Remyelination
por: Wu, Lai Man Natalie, et al.
Publicado: (2016)

Mi-2/NuRD complex protects stem cell progeny from mitogenic Notch signaling
por: Zacharioudaki, Evanthia, et al.
Publicado: (2019)

PWWP2B Fine‐Tunes Adipose Thermogenesis by Stabilizing HDACs in a NuRD Subcomplex
por: Yan, Linyu, et al.
Publicado: (2021)

NuRD‐independent Mi‐2 activity represses ectopic gene expression during neuronal maturation
por: Aughey, Gabriel N, et al.
Publicado: (2023)

NuRD Suppresses Pluripotency Gene Expression to Promote Transcriptional Heterogeneity and Lineage Commitment
por: Reynolds, Nicola, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_j7a2t8ld3u2muoata8tpm41647