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Saccharomyces cerevisiae Est3p dimerizes in vitro and dimerization contributes to efficient telomere replication in vivo
In Saccharomyces cerevisiae at least five genes, EST1, EST2, EST3, TLC1 and CDC13, are required for telomerase activity in vivo. The telomerase catalytic subunit Est2p and telomerase RNA subunit Tlc1 constitute the telomerase core enzyme. Est1p and Est3p are the other subunits of telomerase holoenzy...
Autores principales: | Yang, Cui-Ping, Chen, Yong-Bin, Meng, Fei-Long, Zhou, Jin-Qiu |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1331985/ https://www.ncbi.nlm.nih.gov/pubmed/16418502 http://dx.doi.org/10.1093/nar/gkj445 |
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