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TACC3 mediates the association of MBD2 with histone acetyltransferases and relieves transcriptional repression of methylated promoters
We have recently reported that a novel MBD2 interactor (MBDin) has the capacity to reactivate transcription from MBD2-repressed methylated promoters even in the absence of demethylation events. Here we show that another unrelated protein, TACC3, displays a similar activity on methylated genes. In ad...
Autores principales: | Angrisano, Tiziana, Lembo, Francesca, Pero, Raffaela, Natale, Francesco, Fusco, Alfredo, Avvedimento, Vittorio E., Bruni, Carmelo B., Chiariotti, Lorenzo |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1331987/ https://www.ncbi.nlm.nih.gov/pubmed/16410616 http://dx.doi.org/10.1093/nar/gkj400 |
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