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Differential Susceptibility to Hypertension Is Due to Selection during the Out-of-Africa Expansion

Hypertension is a leading cause of stroke, heart disease, and kidney failure. The genetic basis of blood pressure variation is largely unknown but is likely to involve genes that influence renal salt handling and arterial vessel tone. Here we argue that susceptibility to hypertension is ancestral an...

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Detalles Bibliográficos
Autores principales: Young, J. Hunter, Chang, Yen-Pei C, Kim, James Dae-Ok, Chretien, Jean-Paul, Klag, Michael J, Levine, Michael A, Ruff, Christopher B, Wang, Nae-Yuh, Chakravarti, Aravinda
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1342636/
https://www.ncbi.nlm.nih.gov/pubmed/16429165
http://dx.doi.org/10.1371/journal.pgen.0010082