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A balanced transcription between telomerase and the telomeric DNA-binding proteins TRF1, TRF2 and Pot1 in resting, activated, HTLV-1-transformed and Tax-expressing human T lymphocytes

BACKGROUND: The functional state of human telomeres is controlled by telomerase and by a protein complex named shelterin, including the telomeric DNA-binding proteins TRF1, TRF2 and Pot1 involved in telomere capping functions. The expression of hTERT, encoding the catalytic subunit of telomerase, pl...

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Detalles Bibliográficos
Autores principales: Escoffier, Emmanuelle, Rezza, Amélie, Roborel de Climens, Aude, Belleville, Aurélie, Gazzolo, Louis, Gilson, Eric, Duc Dodon, Madeleine
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1343578/
https://www.ncbi.nlm.nih.gov/pubmed/16354306
http://dx.doi.org/10.1186/1742-4690-2-77