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Unbiased in vitro selection reveals the unique character of the self-cleaving antigenomic HDV RNA sequence
In order to revisit the architecture of the catalytic center of the antigenomic hepatitis delta virus (HDV) ribozyme we developed an unbiased in vitro selection procedure that efficiently selected novel variants from a relatively small set of sequences. Using this procedure we examined all possible...
Autores principales: | Nehdi, Atef, Perreault, Jean-Pierre |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1345697/ https://www.ncbi.nlm.nih.gov/pubmed/16432262 http://dx.doi.org/10.1093/nar/gkj463 |
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