Cargando…
The imprinted gene and parent-of-origin effect database now includes parental origin of de novo mutations
The imprinted gene and parent-of-origin effect database () consists of two sections. One section catalogues the current literature on imprinted genes in humans and animals. The second, and new, section catalogues current reports of parental origin of de novo mutations in humans alone. The addition o...
Autores principales: | , , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2006
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1347463/ https://www.ncbi.nlm.nih.gov/pubmed/16381868 http://dx.doi.org/10.1093/nar/gkj101 |
_version_ | 1782126624547799040 |
---|---|
author | Glaser, Rivka L. Ramsay, Joshua P. Morison, Ian M. |
author_facet | Glaser, Rivka L. Ramsay, Joshua P. Morison, Ian M. |
author_sort | Glaser, Rivka L. |
collection | PubMed |
description | The imprinted gene and parent-of-origin effect database () consists of two sections. One section catalogues the current literature on imprinted genes in humans and animals. The second, and new, section catalogues current reports of parental origin of de novo mutations in humans alone. The addition of a catalogue of de novo mutations that show a parent-of-origin effect expands the scope of the database and provides a useful tool for examining parental origin trends for different types of spontaneous mutations. This new section includes >1700 mutations, found in 59 different disorders. The 85 imprinted genes are described in 152 entries from several mammalian species. In addition, >300 other entries describe a range of reported parent-of-origin effects in animals. |
format | Text |
id | pubmed-1347463 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2006 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-13474632006-01-25 The imprinted gene and parent-of-origin effect database now includes parental origin of de novo mutations Glaser, Rivka L. Ramsay, Joshua P. Morison, Ian M. Nucleic Acids Res Article The imprinted gene and parent-of-origin effect database () consists of two sections. One section catalogues the current literature on imprinted genes in humans and animals. The second, and new, section catalogues current reports of parental origin of de novo mutations in humans alone. The addition of a catalogue of de novo mutations that show a parent-of-origin effect expands the scope of the database and provides a useful tool for examining parental origin trends for different types of spontaneous mutations. This new section includes >1700 mutations, found in 59 different disorders. The 85 imprinted genes are described in 152 entries from several mammalian species. In addition, >300 other entries describe a range of reported parent-of-origin effects in animals. Oxford University Press 2006-01-01 2005-12-28 /pmc/articles/PMC1347463/ /pubmed/16381868 http://dx.doi.org/10.1093/nar/gkj101 Text en © The Author 2006. Published by Oxford University Press. All rights reserved |
spellingShingle | Article Glaser, Rivka L. Ramsay, Joshua P. Morison, Ian M. The imprinted gene and parent-of-origin effect database now includes parental origin of de novo mutations |
title | The imprinted gene and parent-of-origin effect database now includes parental origin of de novo mutations |
title_full | The imprinted gene and parent-of-origin effect database now includes parental origin of de novo mutations |
title_fullStr | The imprinted gene and parent-of-origin effect database now includes parental origin of de novo mutations |
title_full_unstemmed | The imprinted gene and parent-of-origin effect database now includes parental origin of de novo mutations |
title_short | The imprinted gene and parent-of-origin effect database now includes parental origin of de novo mutations |
title_sort | imprinted gene and parent-of-origin effect database now includes parental origin of de novo mutations |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1347463/ https://www.ncbi.nlm.nih.gov/pubmed/16381868 http://dx.doi.org/10.1093/nar/gkj101 |
work_keys_str_mv | AT glaserrivkal theimprintedgeneandparentoforigineffectdatabasenowincludesparentaloriginofdenovomutations AT ramsayjoshuap theimprintedgeneandparentoforigineffectdatabasenowincludesparentaloriginofdenovomutations AT morisonianm theimprintedgeneandparentoforigineffectdatabasenowincludesparentaloriginofdenovomutations AT glaserrivkal imprintedgeneandparentoforigineffectdatabasenowincludesparentaloriginofdenovomutations AT ramsayjoshuap imprintedgeneandparentoforigineffectdatabasenowincludesparentaloriginofdenovomutations AT morisonianm imprintedgeneandparentoforigineffectdatabasenowincludesparentaloriginofdenovomutations |