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ZW10 links mitotic checkpoint signaling to the structural kinetochore
The mitotic checkpoint ensures that chromosomes are divided equally between daughter cells and is a primary mechanism preventing the chromosome instability often seen in aneuploid human tumors. ZW10 and Rod play an essential role in this checkpoint. We show that in mitotic human cells ZW10 resides i...
Autores principales: | Kops, Geert J.P.L., Kim, Yumi, Weaver, Beth A.A., Mao, Yinghui, McLeod, Ian, Yates, John R., Tagaya, Mitsuo, Cleveland, Don W. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1351127/ https://www.ncbi.nlm.nih.gov/pubmed/15824131 http://dx.doi.org/10.1083/jcb.200411118 |
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