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Mutations in the mitochondrial DNA D-loop region are frequent in cervical cancer
BACKGROUND: Mitochondrial DNA (mtDNA) is known for high mutation rates caused by lack of protective histones, inefficient DNA repair systems, and continuous exposure to mutagenic effects of oxygen radicals. Alterations in the non-coding displacement (D) loop of mitochondrial DNA are present in many...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1352382/ https://www.ncbi.nlm.nih.gov/pubmed/16359547 http://dx.doi.org/10.1186/1475-2867-5-34 |