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Prediction of protein structural class with Rough Sets
BACKGROUND: A new method for the prediction of protein structural classes is constructed based on Rough Sets algorithm, which is a rule-based data mining method. Amino acid compositions and 8 physicochemical properties data are used as conditional attributes for the construction of decision system....
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1363362/ https://www.ncbi.nlm.nih.gov/pubmed/16412240 http://dx.doi.org/10.1186/1471-2105-7-20 |
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author | Cao, Youfang Liu, Shi Zhang, Lida Qin, Jie Wang, Jiang Tang, Kexuan |
author_facet | Cao, Youfang Liu, Shi Zhang, Lida Qin, Jie Wang, Jiang Tang, Kexuan |
author_sort | Cao, Youfang |
collection | PubMed |
description | BACKGROUND: A new method for the prediction of protein structural classes is constructed based on Rough Sets algorithm, which is a rule-based data mining method. Amino acid compositions and 8 physicochemical properties data are used as conditional attributes for the construction of decision system. After reducing the decision system, decision rules are generated, which can be used to classify new objects. RESULTS: In this study, self-consistency and jackknife tests on the datasets constructed by G.P. Zhou (Journal of Protein Chemistry, 1998, 17: 729–738) are used to verify the performance of this method, and are compared with some of prior works. The results showed that the rough sets approach is very promising and may play a complementary role to the existing powerful approaches, such as the component-coupled, neural network, SVM, and LogitBoost approaches. CONCLUSION: The results with high success rates indicate that the rough sets approach as proposed in this paper might hold a high potential to become a useful tool in bioinformatics. |
format | Text |
id | pubmed-1363362 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2006 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-13633622006-02-10 Prediction of protein structural class with Rough Sets Cao, Youfang Liu, Shi Zhang, Lida Qin, Jie Wang, Jiang Tang, Kexuan BMC Bioinformatics Research Article BACKGROUND: A new method for the prediction of protein structural classes is constructed based on Rough Sets algorithm, which is a rule-based data mining method. Amino acid compositions and 8 physicochemical properties data are used as conditional attributes for the construction of decision system. After reducing the decision system, decision rules are generated, which can be used to classify new objects. RESULTS: In this study, self-consistency and jackknife tests on the datasets constructed by G.P. Zhou (Journal of Protein Chemistry, 1998, 17: 729–738) are used to verify the performance of this method, and are compared with some of prior works. The results showed that the rough sets approach is very promising and may play a complementary role to the existing powerful approaches, such as the component-coupled, neural network, SVM, and LogitBoost approaches. CONCLUSION: The results with high success rates indicate that the rough sets approach as proposed in this paper might hold a high potential to become a useful tool in bioinformatics. BioMed Central 2006-01-14 /pmc/articles/PMC1363362/ /pubmed/16412240 http://dx.doi.org/10.1186/1471-2105-7-20 Text en Copyright © 2006 Cao et al; licensee BioMed Central Ltd. |
spellingShingle | Research Article Cao, Youfang Liu, Shi Zhang, Lida Qin, Jie Wang, Jiang Tang, Kexuan Prediction of protein structural class with Rough Sets |
title | Prediction of protein structural class with Rough Sets |
title_full | Prediction of protein structural class with Rough Sets |
title_fullStr | Prediction of protein structural class with Rough Sets |
title_full_unstemmed | Prediction of protein structural class with Rough Sets |
title_short | Prediction of protein structural class with Rough Sets |
title_sort | prediction of protein structural class with rough sets |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1363362/ https://www.ncbi.nlm.nih.gov/pubmed/16412240 http://dx.doi.org/10.1186/1471-2105-7-20 |
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