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Successful rescue therapy with tenofovir in a patient with hepatic decompensation and adefovir resistant HBV mutant

BACKGROUND: Prolonged adefovir therapy exposes to the emergence of adefovir resistant hepatitis B virus mutants. Initial reports of the rtN236T mutation showed preserved sensitivity to lamivudine; however, complex mutations are emerging with reduced susceptibility to lamivudine. CASE PRESENTATION: A...

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Detalles Bibliográficos
Autores principales: Ratziu, Vlad, Thibault, Vincent, Benhamou, Yves, Poynard, Thierry
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1363728/
https://www.ncbi.nlm.nih.gov/pubmed/16405720
http://dx.doi.org/10.1186/1476-5926-5-1