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Successful rescue therapy with tenofovir in a patient with hepatic decompensation and adefovir resistant HBV mutant
BACKGROUND: Prolonged adefovir therapy exposes to the emergence of adefovir resistant hepatitis B virus mutants. Initial reports of the rtN236T mutation showed preserved sensitivity to lamivudine; however, complex mutations are emerging with reduced susceptibility to lamivudine. CASE PRESENTATION: A...
Autores principales: | Ratziu, Vlad, Thibault, Vincent, Benhamou, Yves, Poynard, Thierry |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1363728/ https://www.ncbi.nlm.nih.gov/pubmed/16405720 http://dx.doi.org/10.1186/1476-5926-5-1 |
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