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Mechanisms of transcriptional repression of cell-cycle G(2)/M promoters by p63

p63 is a developmentally regulated transcription factor related to p53, which activates and represses specific genes. The human AEC (Ankyloblepharon–Ectodermal dysplasia-Clefting) and EEC (Ectrodactyly–Ectodermal dysplasia–Cleft lip/palate) syndromes are caused by missense mutations of p63, within t...

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Detalles Bibliográficos
Autores principales: Testoni, Barbara, Mantovani, Roberto
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1363772/
https://www.ncbi.nlm.nih.gov/pubmed/16473849
http://dx.doi.org/10.1093/nar/gkj477