Combination of methylated-DNA precipitation and methylation-sensitive restriction enzymes (COMPARE-MS) for the rapid, sensitive and quantitative detection of DNA methylation

Hypermethylation of CpG island (CGI) sequences is a nearly universal somatic genome alteration in cancer. Rapid and sensitive detection of DNA hypermethylation would aid in cancer diagnosis and risk stratification. We present a novel technique, called COMPARE-MS, that can rapidly and quantitatively...

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Detalles Bibliográficos
Autores principales: Yegnasubramanian, Srinivasan, Lin, Xiaohui, Haffner, Michael C., DeMarzo, Angelo M., Nelson, William G.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1363782/
https://www.ncbi.nlm.nih.gov/pubmed/16473842
http://dx.doi.org/10.1093/nar/gnj022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1363782/
https://www.ncbi.nlm.nih.gov/pubmed/16473842
http://dx.doi.org/10.1093/nar/gnj022

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