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Why Do HIV-1 and HIV-2 Use Different Pathways to Develop AZT Resistance?

The human immunodeficiency virus type 1 (HIV-1) develops resistance to all available drugs, including the nucleoside analog reverse transcriptase inhibitors (NRTIs) such as AZT. ATP-mediated excision underlies the most common form of HIV-1 resistance to AZT. However, clinical data suggest that when...

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Detalles Bibliográficos
Autores principales:	Boyer, Paul L, Sarafianos, Stefan G, Clark, Patrick K, Arnold, Eddy, Hughes, Stephen H
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2006
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1364504/ https://www.ncbi.nlm.nih.gov/pubmed/16485036 http://dx.doi.org/10.1371/journal.ppat.0020010

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