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Stable low-level expression of p21(WAF1/CIP1 )in A549 human bronchogenic carcinoma cell line-derived clones down-regulates E2F1 mRNA and restores cell proliferation control

BACKGROUND: Deregulated cell cycle progression and loss of proliferation control are key properties of malignant cells. In previous studies, an interactive transcript abundance index (ITAI) comprising three cell cycle control genes, [MYC × E2F1]/p21 accurately distinguished normal from malignant bro...

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Detalles Bibliográficos
Autores principales:	Graves, Timothy G, Harr, Michael W, Crawford, Erin L, Willey, James C
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2006
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1368995/ https://www.ncbi.nlm.nih.gov/pubmed/16403226 http://dx.doi.org/10.1186/1476-4598-5-1

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