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Allellic variants in regulatory regions of cyclooxygenase-2: association with advanced colorectal adenoma
Cyclooxygenase 2 (Cox-2) is upregulated in colorectal adenomas and carcinomas. Polymorphisms in the Cox-2 gene may influence its function and/or its expression and may modify the protective effect of nonsteroidal anti-inflammatory drugs (NSAIDs), thereby impacting individuals' risk of developin...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2005
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1369968/ https://www.ncbi.nlm.nih.gov/pubmed/16205694 http://dx.doi.org/10.1038/sj.bjc.6602806 |