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Allellic variants in regulatory regions of cyclooxygenase-2: association with advanced colorectal adenoma

Cyclooxygenase 2 (Cox-2) is upregulated in colorectal adenomas and carcinomas. Polymorphisms in the Cox-2 gene may influence its function and/or its expression and may modify the protective effect of nonsteroidal anti-inflammatory drugs (NSAIDs), thereby impacting individuals' risk of developin...

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Detalles Bibliográficos
Autores principales:	Ali, I U, Luke, B T, Dean, M, Greenwald, P
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2005
Materias:	Genetics and Genomics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1369968/ https://www.ncbi.nlm.nih.gov/pubmed/16205694 http://dx.doi.org/10.1038/sj.bjc.6602806

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