Large-Scale Evidence for the Effect of the COLIA1 Sp1 Polymorphism on Osteoporosis Outcomes: The GENOMOS Study

BACKGROUND: Osteoporosis and fracture risk are considered to be under genetic control. Extensive work is being performed to identify the exact genetic variants that determine this risk. Previous work has suggested that a G/T polymorphism affecting an Sp1 binding site in the COLIA1 gene is a genetic...

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Detalles Bibliográficos
Autores principales: Ralston, Stuart H, Uitterlinden, André G, Brandi, Maria Luisa, Balcells, Susana, Langdahl, Bente L, Lips, Paul, Lorenc, Roman, Obermayer-Pietsch, Barbara, Scollen, Serena, Bustamante, Mariona, Husted, Lise Bjerre, Carey, Alisoun H, Diez-Perez, Adolfo, Dunning, Alison M, Falchetti, Alberto, Karczmarewicz, Elzbieta, Kruk, Marcin, van Leeuwen, Johannes P. T. M., van Meurs, Joyce B. J., Mangion, Jon, McGuigan, Fiona E. A, Mellibovsky, Leonardo, del Monte, Francesca, Pols, Huibert A. P, Reeve, Jonathan, Reid, David M, Renner, Wilfried, Rivadeneira, Fernando, van Schoor, Natasja M., Sherlock, Rachael E, Ioannidis, John P. A
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1370920/
https://www.ncbi.nlm.nih.gov/pubmed/16475872
http://dx.doi.org/10.1371/journal.pmed.0030090

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