Loading…
Departure from multiplicative interaction for catechol-O-methyltransferase genotype and active/passive exposure to tobacco smoke among women with breast cancer
BACKGROUND: Women with homozygous polymorphic alleles of catechol-O-methyltransferase (COMT-LL) metabolize 2-hydroxylated estradiol, a suspected anticarcinogenic metabolite of estrogen, at a four-fold lower rate than women with no polymorphic alleles (COMT-HH) or heterozygous women (COMT-HL). We hyp...
Main Authors: | Bradbury, Brian D, Wilk, Jemma B, Aschengrau, Ann, Lash, Timothy L |
---|---|
Format: | Text |
Language: | English |
Published: |
BioMed Central
2006
|
Subjects: | |
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1373621/ https://www.ncbi.nlm.nih.gov/pubmed/16417624 http://dx.doi.org/10.1186/1477-3163-5-3 |
Similar Items
-
A case-only analysis of the interaction between N-acetyltransferase 2 haplotypes and tobacco smoke in breast cancer etiology
by: Lash, Timothy L, et al.
Published: (2005) -
Determination of Methylated CpG Sites in the Promoter Region of Catechol-O-Methyltransferase (COMT) and their Involvement in the Etiology of Tobacco Smoking
by: Xu, Qing, et al.
Published: (2010) -
Roles of functional catechol-O-methyltransferase genotypes in Chinese patients with Parkinson’s disease
by: Xiao, Qin, et al.
Published: (2017) -
Catechol-O-Methyltransferase Genotype, Frailty, and Gait Speed: The Cardiovascular Health Study
by: Mance, Shannon, et al.
Published: (2020) -
Catechol‐O‐Methyltransferase and Cardiovascular Disease: MESA
by: Hall, Kathryn T., et al.
Published: (2019)