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Reduced hippocampal activation during episodic encoding in middle-aged individuals at genetic risk of Alzheimer's Disease: a cross-sectional study

BACKGROUND: The presence of the apolipoprotein E (APOE) ε4 allele is a major risk factor for the development of Alzheimer's disease (AD), and has been associated with metabolic brain changes several years before the onset of typical AD symptoms. Functional MRI (fMRI) is a brain imaging techniqu...

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Detalles Bibliográficos
Autores principales:	Trivedi, Mehul A, Schmitz, Taylor W, Ries, Michele L, Torgerson, Britta M, Sager, Mark A, Hermann, Bruce P, Asthana, Sanjay, Johnson, Sterling C
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2006
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1373642/ https://www.ncbi.nlm.nih.gov/pubmed/16412236 http://dx.doi.org/10.1186/1741-7015-4-1

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