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Actin and agonist MHC–peptide complex–dependent T cell receptor microclusters as scaffolds for signaling
T cell receptor (TCR) microclusters form within seconds of T cell contact with supported planar bilayers containing intercellular adhesion molecule-1 and agonist major histocompatibility complex (MHC)–peptide complexes, and elevation of cytoplasmic Ca(2+) is observed within seconds of the first dete...
Autores principales: | Campi, Gabriele, Varma, Rajat, Dustin, Michael L. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1373686/ https://www.ncbi.nlm.nih.gov/pubmed/16216891 http://dx.doi.org/10.1084/jem.20051182 |
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