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Gene expression patterns vary in clonal cell cultures from Rett syndrome females with eight different MECP2 mutations
BACKGROUND: Females with the neurological disorder Rett syndrome are heterozygous for mutations in X-linked MECP2 that encodes methyl-CpG binding protein 2 (MeCP2) thought to act as a transcriptional repressor. To identify target genes for MeCP2 modulation, we studied global gene expression in singl...
Autores principales: | Traynor, Jeff, Agarwal, Priyanka, Lazzeroni, Laura, Francke, Uta |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC137585/ https://www.ncbi.nlm.nih.gov/pubmed/12418965 http://dx.doi.org/10.1186/1471-2350-3-12 |
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