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Gene expression patterns vary in clonal cell cultures from Rett syndrome females with eight different MECP2 mutations

BACKGROUND: Females with the neurological disorder Rett syndrome are heterozygous for mutations in X-linked MECP2 that encodes methyl-CpG binding protein 2 (MeCP2) thought to act as a transcriptional repressor. To identify target genes for MeCP2 modulation, we studied global gene expression in singl...

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Detalles Bibliográficos
Autores principales: Traynor, Jeff, Agarwal, Priyanka, Lazzeroni, Laura, Francke, Uta
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC137585/
https://www.ncbi.nlm.nih.gov/pubmed/12418965
http://dx.doi.org/10.1186/1471-2350-3-12

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