MCP-1 overexpressed in tuberous sclerosis lesions acts as a paracrine factor for tumor development

Patients with tuberous sclerosis complex (TSC) develop hamartomatous tumors showing loss of function of the tumor suppressor TSC1 (hamartin) or TSC2 (tuberin) and increased angiogenesis, fibrosis, and abundant mononuclear phagocytes. To identify soluble factors with potential roles in TSC tumorigene...

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Detalles Bibliográficos
Autores principales: Li, Shaowei, Takeuchi, Fumiko, Wang, Ji-an, Fuller, Christopher, Pacheco-Rodriguez, Gustavo, Moss, Joel, Darling, Thomas N.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1378109/
https://www.ncbi.nlm.nih.gov/pubmed/16129702
http://dx.doi.org/10.1084/jem.20042469

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1378109/
https://www.ncbi.nlm.nih.gov/pubmed/16129702
http://dx.doi.org/10.1084/jem.20042469

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