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Proapoptotic activity of Ukrain is based on Chelidonium majus L. alkaloids and mediated via a mitochondrial death pathway

BACKGROUND: The anticancer drug Ukrain (NSC-631570) which has been specified by the manufacturer as semisynthetic derivative of the Chelidonium majus L. alkaloid chelidonine and the alkylans thiotepa was reported to exert selective cytotoxic effects on human tumour cell lines in vitro. Few clinical...

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Detalles Bibliográficos
Autores principales:	Habermehl, Daniel, Kammerer, Bernd, Handrick, René, Eldh, Therese, Gruber, Charlotte, Cordes, Nils, Daniel, Peter T, Plasswilm, Ludwig, Bamberg, Michael, Belka, Claus, Jendrossek, Verena
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2006
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1379651/ https://www.ncbi.nlm.nih.gov/pubmed/16417634 http://dx.doi.org/10.1186/1471-2407-6-14

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