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Phosphodiesterase type 4 expression and anti-proliferative effects in human pulmonary artery smooth muscle cells
BACKGROUND: Pulmonary arterial hypertension is a proliferative vascular disease, characterized by aberrant regulation of smooth muscle cell proliferation and apoptosis in distal pulmonary arteries. Prostacyclin (PGI(2)) analogues have anti-proliferative effects on distal human pulmonary artery smoot...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1386664/ https://www.ncbi.nlm.nih.gov/pubmed/16423283 http://dx.doi.org/10.1186/1465-9921-7-9 |