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Phosphodiesterase type 4 expression and anti-proliferative effects in human pulmonary artery smooth muscle cells

BACKGROUND: Pulmonary arterial hypertension is a proliferative vascular disease, characterized by aberrant regulation of smooth muscle cell proliferation and apoptosis in distal pulmonary arteries. Prostacyclin (PGI(2)) analogues have anti-proliferative effects on distal human pulmonary artery smoot...

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Detalles Bibliográficos
Autores principales:	Growcott, Ellena J, Spink, Karen G, Ren, Xiaohui, Afzal, Saliha, Banner, Kathy H, Wharton, John
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2006
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1386664/ https://www.ncbi.nlm.nih.gov/pubmed/16423283 http://dx.doi.org/10.1186/1465-9921-7-9

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