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The mammary myoepithelial cell - Cinderella or ugly sister?
The breast myoepithelial cell is the Cinderella of mammary biology. Although its contribution to benign and some malignant pathologies is recognised, it has been largely neglected in molecular and biological studies. The reason for this has been the perception that its role in normal physiology is c...
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2001
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC138667/ https://www.ncbi.nlm.nih.gov/pubmed/11250738 http://dx.doi.org/10.1186/bcr260 |
| _version_ | 1782120469350055936 |
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| author | Lakhani, Sunil R O'Hare, Michael J |
| author_facet | Lakhani, Sunil R O'Hare, Michael J |
| author_sort | Lakhani, Sunil R |
| collection | PubMed |
| description | The breast myoepithelial cell is the Cinderella of mammary biology. Although its contribution to benign and some malignant pathologies is recognised, it has been largely neglected in molecular and biological studies. The reason for this has been the perception that its role in normal physiology is confined to lactation and the belief that most breast cancers arise from luminal epithelial cells. This review presents our perspective on its broader biological significance and its potential use as a model system for understanding breast carcinogenesis. |
| format | Text |
| id | pubmed-138667 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2001 |
| publisher | BioMed Central |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-1386672003-02-27 The mammary myoepithelial cell - Cinderella or ugly sister? Lakhani, Sunil R O'Hare, Michael J Breast Cancer Res Commentary The breast myoepithelial cell is the Cinderella of mammary biology. Although its contribution to benign and some malignant pathologies is recognised, it has been largely neglected in molecular and biological studies. The reason for this has been the perception that its role in normal physiology is confined to lactation and the belief that most breast cancers arise from luminal epithelial cells. This review presents our perspective on its broader biological significance and its potential use as a model system for understanding breast carcinogenesis. BioMed Central 2001 2000-11-02 /pmc/articles/PMC138667/ /pubmed/11250738 http://dx.doi.org/10.1186/bcr260 Text en Copyright © 2000 BioMed Central Ltd on behalf of the copyright holders |
| spellingShingle | Commentary Lakhani, Sunil R O'Hare, Michael J The mammary myoepithelial cell - Cinderella or ugly sister? |
| title | The mammary myoepithelial cell - Cinderella or ugly sister? |
| title_full | The mammary myoepithelial cell - Cinderella or ugly sister? |
| title_fullStr | The mammary myoepithelial cell - Cinderella or ugly sister? |
| title_full_unstemmed | The mammary myoepithelial cell - Cinderella or ugly sister? |
| title_short | The mammary myoepithelial cell - Cinderella or ugly sister? |
| title_sort | mammary myoepithelial cell - cinderella or ugly sister? |
| topic | Commentary |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC138667/ https://www.ncbi.nlm.nih.gov/pubmed/11250738 http://dx.doi.org/10.1186/bcr260 |
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