Hypoxia and oxidative stress in breast cancer: Hypoxia signalling pathways

Hypoxia-inducible factor-1 (HIF), which is centrally involved in physiological oxygen homeostasis, is also activated in the majority of tumours. Activation of HIF can occur through genetic mechanisms or as a result of hypoxia within the tumour microenvironment. In some cases HIF activation appears t...

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Detalles Bibliográficos
Autores principales: Pugh, Christopher W, Gleadle, Jonathan, Maxwell, Patrick H
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2001
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC138694/
https://www.ncbi.nlm.nih.gov/pubmed/11597320

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