Absence of p53 in Clara cells favours multinucleation and loss of cell cycle arrest

BACKGROUND: The p53 oncosuppressor protein is a critical mediator of the response to injury in mammalian cells and is mutationally inactivated in the majority of lung malignancies. In this analysis, the effects of p53-deficiency were investigated in short-term primary cultures of murine bronchiolar...

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Detalles Bibliográficos
Autores principales: Armit, Christopher J, O'Dea, Shirley, Clarke, Alan R, Harrison, David J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2002
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC138798/
https://www.ncbi.nlm.nih.gov/pubmed/12443538
http://dx.doi.org/10.1186/1471-2121-3-27

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC138798/
https://www.ncbi.nlm.nih.gov/pubmed/12443538
http://dx.doi.org/10.1186/1471-2121-3-27

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