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Simultaneous localization of MLL, AF4 and ENL genes in interphase nuclei by 3D-FISH: MLL translocation revisited

BACKGROUND: Haematological cancer is characterised by chromosomal translocation (e.g. MLL translocation in acute leukaemia) and two models have been proposed to explain the origins of recurrent reciprocal translocation. The first, established from pairs of translocated genes (such as BCR and ABL), c...

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Detalles Bibliográficos
Autores principales: Gué, Michaël, Sun, Jian-Sheng, Boudier, Thomas
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1388228/
https://www.ncbi.nlm.nih.gov/pubmed/16433901
http://dx.doi.org/10.1186/1471-2407-6-20