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Coordinate enhancement of transgene transcription and translation in a lentiviral vector

BACKGROUND: Coordinate enhancement of transgene transcription and translation would be a potent approach to significantly improve protein output in a broad array of viral vectors and nonviral expression systems. Many vector transgenes are complementary DNA (cDNA). The lack of splicing can significan...

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Detalles Bibliográficos
Autores principales: Yilmaz, Alper, Fernandez, Soledad, Lairmore, Michael D, Boris-Lawrie, Kathleen
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1388234/
https://www.ncbi.nlm.nih.gov/pubmed/16480517
http://dx.doi.org/10.1186/1742-4690-3-13