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An overview of the structures of protein-DNA complexes

On the basis of a structural analysis of 240 protein-DNA complexes contained in the Protein Data Bank (PDB), we have classified the DNA-binding proteins involved into eight different structural/functional groups, which are further classified into 54 structural families. Here we present this classifi...

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Detalles Bibliográficos
Autores principales: Luscombe, Nicholas M, Austin, Susan E, Berman , Helen M, Thornton, Janet M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC138832/
https://www.ncbi.nlm.nih.gov/pubmed/11104519
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author Luscombe, Nicholas M
Austin, Susan E
Berman , Helen M
Thornton, Janet M
author_facet Luscombe, Nicholas M
Austin, Susan E
Berman , Helen M
Thornton, Janet M
author_sort Luscombe, Nicholas M
collection PubMed
description On the basis of a structural analysis of 240 protein-DNA complexes contained in the Protein Data Bank (PDB), we have classified the DNA-binding proteins involved into eight different structural/functional groups, which are further classified into 54 structural families. Here we present this classification and review the functions, structures and binding interactions of these protein-DNA complexes.
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spelling pubmed-1388322003-02-28 An overview of the structures of protein-DNA complexes Luscombe, Nicholas M Austin, Susan E Berman , Helen M Thornton, Janet M Genome Biol Review On the basis of a structural analysis of 240 protein-DNA complexes contained in the Protein Data Bank (PDB), we have classified the DNA-binding proteins involved into eight different structural/functional groups, which are further classified into 54 structural families. Here we present this classification and review the functions, structures and binding interactions of these protein-DNA complexes. BioMed Central 2000 2000-06-09 /pmc/articles/PMC138832/ /pubmed/11104519 Text en Copyright © 2000 GenomeBiology.com
spellingShingle Review
Luscombe, Nicholas M
Austin, Susan E
Berman , Helen M
Thornton, Janet M
An overview of the structures of protein-DNA complexes
title An overview of the structures of protein-DNA complexes
title_full An overview of the structures of protein-DNA complexes
title_fullStr An overview of the structures of protein-DNA complexes
title_full_unstemmed An overview of the structures of protein-DNA complexes
title_short An overview of the structures of protein-DNA complexes
title_sort overview of the structures of protein-dna complexes
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC138832/
https://www.ncbi.nlm.nih.gov/pubmed/11104519
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