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Secret sharers in the immune system: a novel RNA editing activity links switch recombination and somatic hypermutation
A new mechanism for regulation in the immune system has been identified: a cytidine deaminase is critical for both class switch recombination and somatic hypermutation, revealing an unanticipated link between these two processes.
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2000
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC138873/ https://www.ncbi.nlm.nih.gov/pubmed/11178252 |
| _version_ | 1782120512653099008 |
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| author | Maizels, Nancy |
| author_facet | Maizels, Nancy |
| author_sort | Maizels, Nancy |
| collection | PubMed |
| description | A new mechanism for regulation in the immune system has been identified: a cytidine deaminase is critical for both class switch recombination and somatic hypermutation, revealing an unanticipated link between these two processes. |
| format | Text |
| id | pubmed-138873 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2000 |
| publisher | BioMed Central |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-1388732003-03-03 Secret sharers in the immune system: a novel RNA editing activity links switch recombination and somatic hypermutation Maizels, Nancy Genome Biol Minireview A new mechanism for regulation in the immune system has been identified: a cytidine deaminase is critical for both class switch recombination and somatic hypermutation, revealing an unanticipated link between these two processes. BioMed Central 2000 2000-10-13 /pmc/articles/PMC138873/ /pubmed/11178252 Text en Copyright © 2000 GenomeBiology.com |
| spellingShingle | Minireview Maizels, Nancy Secret sharers in the immune system: a novel RNA editing activity links switch recombination and somatic hypermutation |
| title | Secret sharers in the immune system: a novel RNA editing activity links switch recombination and somatic hypermutation |
| title_full | Secret sharers in the immune system: a novel RNA editing activity links switch recombination and somatic hypermutation |
| title_fullStr | Secret sharers in the immune system: a novel RNA editing activity links switch recombination and somatic hypermutation |
| title_full_unstemmed | Secret sharers in the immune system: a novel RNA editing activity links switch recombination and somatic hypermutation |
| title_short | Secret sharers in the immune system: a novel RNA editing activity links switch recombination and somatic hypermutation |
| title_sort | secret sharers in the immune system: a novel rna editing activity links switch recombination and somatic hypermutation |
| topic | Minireview |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC138873/ https://www.ncbi.nlm.nih.gov/pubmed/11178252 |
| work_keys_str_mv | AT maizelsnancy secretsharersintheimmunesystemanovelrnaeditingactivitylinksswitchrecombinationandsomatichypermutation |