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Can sequence determine function?

The functional annotation of proteins identified in genome sequencing projects is based on similarities to homologs in the databases. As a result of the possible strategies for divergent evolution, homologous enzymes frequently do not catalyze the same reaction, and we conclude that assignment of fu...

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Detalles Bibliográficos
Autores principales: Gerlt, John A, Babbitt, Patricia C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC138884/
https://www.ncbi.nlm.nih.gov/pubmed/11178260

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