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Can sequence determine function?
The functional annotation of proteins identified in genome sequencing projects is based on similarities to homologs in the databases. As a result of the possible strategies for divergent evolution, homologous enzymes frequently do not catalyze the same reaction, and we conclude that assignment of fu...
Autores principales: | Gerlt, John A, Babbitt, Patricia C |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2000
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC138884/ https://www.ncbi.nlm.nih.gov/pubmed/11178260 |
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