Multiple RNA-protein interactions in Drosophila dosage compensation

From worms to humans, recognizing and modifying a specific chromosome is essential for dosage compensation, the mechanism by which equal X-linked gene expression in males and females is achieved. Recent molecular genetic and biochemical studies have provided new insights into how regulatory factors...

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Detalles Bibliográficos
Autor principal: Amrein, Hubert
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2000
Materias:
Minireview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC138894/
https://www.ncbi.nlm.nih.gov/pubmed/11178270
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author Amrein, Hubert
author_facet Amrein, Hubert
author_sort Amrein, Hubert
collection PubMed
description From worms to humans, recognizing and modifying a specific chromosome is essential for dosage compensation, the mechanism by which equal X-linked gene expression in males and females is achieved. Recent molecular genetic and biochemical studies have provided new insights into how regulatory factors in Drosophila are recruited and assembled on the X chromosome, leading to the essential hypertranscription of its genes.
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spelling pubmed-1388942003-03-03 Multiple RNA-protein interactions in Drosophila dosage compensation Amrein, Hubert Genome Biol Minireview From worms to humans, recognizing and modifying a specific chromosome is essential for dosage compensation, the mechanism by which equal X-linked gene expression in males and females is achieved. Recent molecular genetic and biochemical studies have provided new insights into how regulatory factors in Drosophila are recruited and assembled on the X chromosome, leading to the essential hypertranscription of its genes. BioMed Central 2000 2000-12-06 /pmc/articles/PMC138894/ /pubmed/11178270 Text en Copyright © 2000 GenomeBiology.com
spellingShingle Minireview
Amrein, Hubert
Multiple RNA-protein interactions in Drosophila dosage compensation
title Multiple RNA-protein interactions in Drosophila dosage compensation
title_full Multiple RNA-protein interactions in Drosophila dosage compensation
title_fullStr Multiple RNA-protein interactions in Drosophila dosage compensation
title_full_unstemmed Multiple RNA-protein interactions in Drosophila dosage compensation
title_short Multiple RNA-protein interactions in Drosophila dosage compensation
title_sort multiple rna-protein interactions in drosophila dosage compensation
topic Minireview
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC138894/
https://www.ncbi.nlm.nih.gov/pubmed/11178270
work_keys_str_mv AT amreinhubert multiplernaproteininteractionsindrosophiladosagecompensation

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