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Morpholino antisense oligonucleotides: tools for investigating vertebrate development
Antisense oligonucleotides provide a promising approach to investigating gene function in vivo, but their ability to offer unambiguous insights into phenotypes has been debated. The recent use of morpholino antisense oligonucleotides in zebrafish embryos may prove a major advance, but rigorous contr...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2001
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC138935/ https://www.ncbi.nlm.nih.gov/pubmed/11387041 |
| _version_ | 1782120527695970304 |
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| author | Corey, David R Abrams, John M |
| author_facet | Corey, David R Abrams, John M |
| author_sort | Corey, David R |
| collection | PubMed |
| description | Antisense oligonucleotides provide a promising approach to investigating gene function in vivo, but their ability to offer unambiguous insights into phenotypes has been debated. The recent use of morpholino antisense oligonucleotides in zebrafish embryos may prove a major advance, but rigorous controls are essential. |
| format | Text |
| id | pubmed-138935 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2001 |
| publisher | BioMed Central |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-1389352003-03-03 Morpholino antisense oligonucleotides: tools for investigating vertebrate development Corey, David R Abrams, John M Genome Biol Minireview Antisense oligonucleotides provide a promising approach to investigating gene function in vivo, but their ability to offer unambiguous insights into phenotypes has been debated. The recent use of morpholino antisense oligonucleotides in zebrafish embryos may prove a major advance, but rigorous controls are essential. BioMed Central 2001 2001-04-26 /pmc/articles/PMC138935/ /pubmed/11387041 Text en Copyright © 2001 BioMed Central Ltd |
| spellingShingle | Minireview Corey, David R Abrams, John M Morpholino antisense oligonucleotides: tools for investigating vertebrate development |
| title | Morpholino antisense oligonucleotides: tools for investigating vertebrate development |
| title_full | Morpholino antisense oligonucleotides: tools for investigating vertebrate development |
| title_fullStr | Morpholino antisense oligonucleotides: tools for investigating vertebrate development |
| title_full_unstemmed | Morpholino antisense oligonucleotides: tools for investigating vertebrate development |
| title_short | Morpholino antisense oligonucleotides: tools for investigating vertebrate development |
| title_sort | morpholino antisense oligonucleotides: tools for investigating vertebrate development |
| topic | Minireview |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC138935/ https://www.ncbi.nlm.nih.gov/pubmed/11387041 |
| work_keys_str_mv | AT coreydavidr morpholinoantisenseoligonucleotidestoolsforinvestigatingvertebratedevelopment AT abramsjohnm morpholinoantisenseoligonucleotidestoolsforinvestigatingvertebratedevelopment |