New clues to the puzzle of mammalian sex determination

WT1 and SOX9 are transcription factors with critical roles in mammalian sex determination and gonadal development. Recent studies in vivo clarify the roles of two alternative splice isoforms of WT1, and demonstrate that SOX9 can induce male sex determination.

Detalles Bibliográficos
Autores principales: Bowles, Josephine, Koopman, Peter
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2001
Materias:
Minireview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC138963/
https://www.ncbi.nlm.nih.gov/pubmed/11574062
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author Bowles, Josephine
Koopman, Peter
author_facet Bowles, Josephine
Koopman, Peter
author_sort Bowles, Josephine
collection PubMed
description WT1 and SOX9 are transcription factors with critical roles in mammalian sex determination and gonadal development. Recent studies in vivo clarify the roles of two alternative splice isoforms of WT1, and demonstrate that SOX9 can induce male sex determination.
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spelling pubmed-1389632003-03-03 New clues to the puzzle of mammalian sex determination Bowles, Josephine Koopman, Peter Genome Biol Minireview WT1 and SOX9 are transcription factors with critical roles in mammalian sex determination and gonadal development. Recent studies in vivo clarify the roles of two alternative splice isoforms of WT1, and demonstrate that SOX9 can induce male sex determination. BioMed Central 2001 2001-08-29 /pmc/articles/PMC138963/ /pubmed/11574062 Text en Copyright © 2001 BioMed Central Ltd
spellingShingle Minireview
Bowles, Josephine
Koopman, Peter
New clues to the puzzle of mammalian sex determination
title New clues to the puzzle of mammalian sex determination
title_full New clues to the puzzle of mammalian sex determination
title_fullStr New clues to the puzzle of mammalian sex determination
title_full_unstemmed New clues to the puzzle of mammalian sex determination
title_short New clues to the puzzle of mammalian sex determination
title_sort new clues to the puzzle of mammalian sex determination
topic Minireview
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC138963/
https://www.ncbi.nlm.nih.gov/pubmed/11574062
work_keys_str_mv AT bowlesjosephine newcluestothepuzzleofmammaliansexdetermination
AT koopmanpeter newcluestothepuzzleofmammaliansexdetermination

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