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New clues to the puzzle of mammalian sex determination

WT1 and SOX9 are transcription factors with critical roles in mammalian sex determination and gonadal development. Recent studies in vivo clarify the roles of two alternative splice isoforms of WT1, and demonstrate that SOX9 can induce male sex determination.

Detalles Bibliográficos
Autores principales: Bowles, Josephine, Koopman, Peter
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC138963/
https://www.ncbi.nlm.nih.gov/pubmed/11574062