Having a BLAST with bioinformatics (and avoiding BLASTphemy)

Searching for similarities between biological sequences is the principal means by which bioinformatics contributes to our understanding of biology. Of the various informatics tools developed to accomplish this task, the most widely used is BLAST, the basic local alignment search tool. This article d...

Descripción completa

Detalles Bibliográficos
Autores principales: Pertsemlidis, Alexander, Fondon, John W
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2001
Materias:
Tutorial
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC138974/
https://www.ncbi.nlm.nih.gov/pubmed/11597340
Descripción
Sumario:Searching for similarities between biological sequences is the principal means by which bioinformatics contributes to our understanding of biology. Of the various informatics tools developed to accomplish this task, the most widely used is BLAST, the basic local alignment search tool. This article discusses the principles, workings, applications and potential pitfalls of BLAST, focusing on the implementation developed at the National Center for Biotechnology Information.

Ejemplares similares