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Having a BLAST with bioinformatics (and avoiding BLASTphemy)
Searching for similarities between biological sequences is the principal means by which bioinformatics contributes to our understanding of biology. Of the various informatics tools developed to accomplish this task, the most widely used is BLAST, the basic local alignment search tool. This article d...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2001
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC138974/ https://www.ncbi.nlm.nih.gov/pubmed/11597340 |
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author | Pertsemlidis, Alexander Fondon, John W |
author_facet | Pertsemlidis, Alexander Fondon, John W |
author_sort | Pertsemlidis, Alexander |
collection | PubMed |
description | Searching for similarities between biological sequences is the principal means by which bioinformatics contributes to our understanding of biology. Of the various informatics tools developed to accomplish this task, the most widely used is BLAST, the basic local alignment search tool. This article discusses the principles, workings, applications and potential pitfalls of BLAST, focusing on the implementation developed at the National Center for Biotechnology Information. |
format | Text |
id | pubmed-138974 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2001 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-1389742003-03-03 Having a BLAST with bioinformatics (and avoiding BLASTphemy) Pertsemlidis, Alexander Fondon, John W Genome Biol Tutorial Searching for similarities between biological sequences is the principal means by which bioinformatics contributes to our understanding of biology. Of the various informatics tools developed to accomplish this task, the most widely used is BLAST, the basic local alignment search tool. This article discusses the principles, workings, applications and potential pitfalls of BLAST, focusing on the implementation developed at the National Center for Biotechnology Information. BioMed Central 2001 2001-09-27 /pmc/articles/PMC138974/ /pubmed/11597340 Text en Copyright © 2001 BioMed Central Ltd |
spellingShingle | Tutorial Pertsemlidis, Alexander Fondon, John W Having a BLAST with bioinformatics (and avoiding BLASTphemy) |
title | Having a BLAST with bioinformatics (and avoiding BLASTphemy) |
title_full | Having a BLAST with bioinformatics (and avoiding BLASTphemy) |
title_fullStr | Having a BLAST with bioinformatics (and avoiding BLASTphemy) |
title_full_unstemmed | Having a BLAST with bioinformatics (and avoiding BLASTphemy) |
title_short | Having a BLAST with bioinformatics (and avoiding BLASTphemy) |
title_sort | having a blast with bioinformatics (and avoiding blastphemy) |
topic | Tutorial |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC138974/ https://www.ncbi.nlm.nih.gov/pubmed/11597340 |
work_keys_str_mv | AT pertsemlidisalexander havingablastwithbioinformaticsandavoidingblastphemy AT fondonjohnw havingablastwithbioinformaticsandavoidingblastphemy |