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HIV: master of the host cell
The human immunodeficiency virus has evolved various mechanisms to exploit its host cells, including the interruption and augmentation of signal transduction pathways. Recently, two DNA microarray studies have illustrated a remarkably broad-based perturbation in host transcriptional responses, which...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2001
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC138982/ https://www.ncbi.nlm.nih.gov/pubmed/11737949 |
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author | Arendt, Christopher W Littman, Dan R |
author_facet | Arendt, Christopher W Littman, Dan R |
author_sort | Arendt, Christopher W |
collection | PubMed |
description | The human immunodeficiency virus has evolved various mechanisms to exploit its host cells, including the interruption and augmentation of signal transduction pathways. Recently, two DNA microarray studies have illustrated a remarkably broad-based perturbation in host transcriptional responses, which is in part mediated by the HIV-encoded Nef protein. HIV therefore seems to function as a 'master regulator' of cellular gene expression. |
format | Text |
id | pubmed-138982 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2001 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-1389822003-03-03 HIV: master of the host cell Arendt, Christopher W Littman, Dan R Genome Biol Minireview The human immunodeficiency virus has evolved various mechanisms to exploit its host cells, including the interruption and augmentation of signal transduction pathways. Recently, two DNA microarray studies have illustrated a remarkably broad-based perturbation in host transcriptional responses, which is in part mediated by the HIV-encoded Nef protein. HIV therefore seems to function as a 'master regulator' of cellular gene expression. BioMed Central 2001 2001-10-22 /pmc/articles/PMC138982/ /pubmed/11737949 Text en Copyright © 2001 BioMed Central Ltd |
spellingShingle | Minireview Arendt, Christopher W Littman, Dan R HIV: master of the host cell |
title | HIV: master of the host cell |
title_full | HIV: master of the host cell |
title_fullStr | HIV: master of the host cell |
title_full_unstemmed | HIV: master of the host cell |
title_short | HIV: master of the host cell |
title_sort | hiv: master of the host cell |
topic | Minireview |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC138982/ https://www.ncbi.nlm.nih.gov/pubmed/11737949 |
work_keys_str_mv | AT arendtchristopherw hivmasterofthehostcell AT littmandanr hivmasterofthehostcell |