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HIV: master of the host cell

The human immunodeficiency virus has evolved various mechanisms to exploit its host cells, including the interruption and augmentation of signal transduction pathways. Recently, two DNA microarray studies have illustrated a remarkably broad-based perturbation in host transcriptional responses, which...

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Detalles Bibliográficos
Autores principales: Arendt, Christopher W, Littman, Dan R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC138982/
https://www.ncbi.nlm.nih.gov/pubmed/11737949
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author Arendt, Christopher W
Littman, Dan R
author_facet Arendt, Christopher W
Littman, Dan R
author_sort Arendt, Christopher W
collection PubMed
description The human immunodeficiency virus has evolved various mechanisms to exploit its host cells, including the interruption and augmentation of signal transduction pathways. Recently, two DNA microarray studies have illustrated a remarkably broad-based perturbation in host transcriptional responses, which is in part mediated by the HIV-encoded Nef protein. HIV therefore seems to function as a 'master regulator' of cellular gene expression.
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spelling pubmed-1389822003-03-03 HIV: master of the host cell Arendt, Christopher W Littman, Dan R Genome Biol Minireview The human immunodeficiency virus has evolved various mechanisms to exploit its host cells, including the interruption and augmentation of signal transduction pathways. Recently, two DNA microarray studies have illustrated a remarkably broad-based perturbation in host transcriptional responses, which is in part mediated by the HIV-encoded Nef protein. HIV therefore seems to function as a 'master regulator' of cellular gene expression. BioMed Central 2001 2001-10-22 /pmc/articles/PMC138982/ /pubmed/11737949 Text en Copyright © 2001 BioMed Central Ltd
spellingShingle Minireview
Arendt, Christopher W
Littman, Dan R
HIV: master of the host cell
title HIV: master of the host cell
title_full HIV: master of the host cell
title_fullStr HIV: master of the host cell
title_full_unstemmed HIV: master of the host cell
title_short HIV: master of the host cell
title_sort hiv: master of the host cell
topic Minireview
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC138982/
https://www.ncbi.nlm.nih.gov/pubmed/11737949
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