Sustained expansion of NKT cells and antigen-specific T cells after injection of α-galactosyl-ceramide loaded mature dendritic cells in cancer patients

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Natural killer T (NKT) cells are distinct glycolipid reactive innate lymphocytes that are implicated in the resistance to pathogens and tumors. Earlier attempts to mobilize NKT cells, specifically, in vivo in humans met with limited success. Here, we evaluated intravenous injection of monocyte-deriv...

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Detalles Bibliográficos
Autores principales: Chang, David H., Osman, Keren, Connolly, John, Kukreja, Anjli, Krasovsky, Joseph, Pack, Maggi, Hutchinson, Aisha, Geller, Matthew, Liu, Nancy, Annable, Rebecca, Shay, Jennifer, Kirchhoff, Kelly, Nishi, Nobusuke, Ando, Yoshitaka, Hayashi, Kunihiko, Hassoun, Hani, Steinman, Ralph M., Dhodapkar, Madhav V.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1389847/
https://www.ncbi.nlm.nih.gov/pubmed/15867097
http://dx.doi.org/10.1084/jem.20042592

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