Genetic Analysis of the Capsular Biosynthetic Locus from All 90 Pneumococcal Serotypes

Several major invasive bacterial pathogens are encapsulated. Expression of a polysaccharide capsule is essential for survival in the blood, and thus for virulence, but also is a target for host antibodies and the basis for effective vaccines. Encapsulated species typically exhibit antigenic variatio...

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Detalles Bibliográficos
Autores principales: Bentley, Stephen D, Aanensen, David M, Mavroidi, Angeliki, Saunders, David, Rabbinowitsch, Ester, Collins, Matthew, Donohoe, Kathy, Harris, David, Murphy, Lee, Quail, Michael A, Samuel, Gabby, Skovsted, Ian C, Kaltoft, Margit Staum, Barrell, Bart, Reeves, Peter R, Parkhill, Julian, Spratt, Brian G
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1391919/
https://www.ncbi.nlm.nih.gov/pubmed/16532061
http://dx.doi.org/10.1371/journal.pgen.0020031

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