P53 autoantibodies in 1006 patients followed up for breast cancer

INTRODUCTION: Dysfunction of the tumour-suppressor protein, p53, may be due to either mutational or epigenetic factors, each of which may lead to accumulation of cytoplasmic p53. Abnormal accumulation of p53 in breast cancer tissue is predictive of poor prognosis [1,2]. Humoral studies [3,4] have sh...

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Detalles Bibliográficos
Autores principales: Metcalfe, Su, Wheeler, Terence K, Picken, Sheila, Negus , Susanne, Jo Milner, A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2000
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13921/
https://www.ncbi.nlm.nih.gov/pubmed/11056691

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